New therapy for childhood neuroblastoma proves feasible and safe
A new treatment option may soon be available for children with neuroblastoma according to research published in the July issue of The Journal of Nuclear Medicine. The study tested the principle that...
View ArticleTwo genes linked to why telomeres stretch in cancer cells
Scientists at Johns Hopkins have provided more clues to one of the least understood phenomena in some cancers: why the "ends caps" of cellular DNA, called telomeres, lengthen instead of shorten.
View ArticleBenefits of radionuclide therapy for neuroendocrine tumors
According to new Dutch research featured in the September issue of The Journal of Nuclear Medicine, a peptide receptor radiolabeled therapy (PRRT), [177Lu-DOTA0,Tyr3]Octreotate (177Lu-octreotate) , is...
View ArticleResearchers discover Achilles' heel in lethal form of prostate cancer
An international team of researchers led by clinicians at Weill Cornell Medical College have discovered a genetic Achilles' heel in an aggressive type of prostate cancer -- a vulnerability they say can...
View ArticleEverolimus prolongs progression-free survival for patients with...
Combination treatment with everolimus, an inhibitor of the mammalian target rapamycin (mTOR), and octreotide has shown to improve progression-free survival for patients with advanced neuroendocrine...
View ArticleResearchers validate staging classifications for neuroendocrine pancreatic...
Researchers at Moffitt Cancer Center have carried out a study to validate the utility of new tumor classification systems for staging and predicting relapse-free survival for patients with...
View ArticleBlood test provides 'snapshot' of tumor drug response
(Medical Xpress) -- Counting the number of tumour cells in blood samples taken before and after treatment for advanced neuroendocrine tumors could provide a snapshot of how well patients are...
View ArticlePET imaging could lead to better care for neuroendocrine cancer
A method of molecular imaging that pinpoints hormonally active tissues in the body could change the course of treatment for a remarkable number of neuroendocrine cancer patients, say researchers at the...
View ArticleChemo combo promising for pancreatic neuroendocrine tumors
(HealthDay) -- The combination of temozolomide and bevacizumab seems to benefit patients with advanced pancreatic neuroendocrine tumors (NETs), according to a study published online July 9 in the...
View ArticleResearchers test new drug for patients with neuroendocrine tumors
A researcher at Moffitt Cancer Center and his international team of colleagues have reported study results on a novel multireceptor-targeted somatostatin analogue called pasireotide (SOM230)...
View ArticleCan the addition of radiolabeled treatments improve outcomes in advanced...
Radiolabeled agents are powerful tools for targeting and killing cancer cells and may help improve outcomes and lengthen survival times of patients with advanced disease that has spread beyond the...
View ArticleResearch suggests popular diabetes drugs can cause abnormal pancreatic growth...
(Medical Xpress)—Individuals who had taken a type of drug commonly used to treat Type 2 diabetes showed abnormalities in the pancreas, including cell proliferation, that may be associated with an...
View ArticleResearchers discover link between inherited endocrine tumor syndrome and...
(Medical Xpress)—A mutation in a protein called menin causes a hereditary cancer syndrome called MEN1 (multiple endocrine neoplasia type 1). Individuals with MEN1 are at a substantially increased risk...
View ArticleCedars-Sinai opens first-of-its-kind trial in western US for metastatic...
Working to improve treatment and survivorship outcomes, the Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute has opened a Phase III clinical trial of targeted radiation for patients with...
View ArticleRadiopeptide therapy improves survival outcomes for neuroendocrine cancer...
Peptide-receptor radionuclide therapy (PRRT) has been a subject of growing research on neuroendocrine tumors, which take up residence in a variety of organs replete with nerve cells that respond to...
View ArticleScientists identified T372R mutation as potential target for diagnosis and...
Chinese researchers from Rui-Jin Hospital, Shanghai Jiao-Tong University School of Medicine, BGI and other institutes identified the recurrent T372R mutation in the transcription factor YY1 (Yin Yang...
View ArticleChemo-radionuclide therapy halts neuroendocrine cancer
Advanced cancer of the neuroendocrine system can lead to dismal prognoses, but a novel therapy is packing a punch by uniting powerful radionuclide treatment and chemotherapy drugs, revealed researchers...
View ArticleLanreotide improves survival with enteropancreatic tumors
(HealthDay)—Lanreotide significantly improves survival among patients with metastatic enteropancreatic neuroendocrine tumors (grade 1 or 2), according to a study published in the July 17 issue of the...
View ArticleMutated ATRX gene linked to brain tumors potential biomarker for rare adrenal...
A somatic mutation in the ATRX gene has recently been shown as a potential molecular marker for aggressive brain tumors, such as gliomas, neuroblastomas and pancreatic neuroendocrine tumors. Now, for...
View ArticlePET/CT captures hidden source of neuroendocrine cancer
The origin of cancer is often obscured by metastases—tumors that have already spread to other tissues. This is especially the case for neuroendocrine tumors (NETs), a malignancy of nerve cells...
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